P73: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_2xwc| PDB=2xwc | SIZE=400| SCENE= |right|CAPTION=Monomer of the dimeric human p73 DNA-binding domain complex with Tris, glycerol and Zn+2 ion (grey), [[2xwc]] }} | {{STRUCTURE_2xwc| PDB=2xwc | SIZE=400| SCENE= |right|CAPTION=Monomer of the dimeric human p73 DNA-binding domain complex with Tris, glycerol and Zn+2 ion (grey), [[2xwc]] }} | ||
'''p73''' is a protein related to p53 tumor suppressor. It is involved in cell cycle regulation and induction of apoptosis. | '''p73''' is a protein related to p53 tumor suppressor. It is involved in cell cycle regulation and induction of apoptosis<ref>PMID:9891077</ref>. p73 has several variants differing in their C- or N-terminal. p73 contains DNA-binding domain (DBD residues 112-312); tetramerization domain (TD residues 351-398). | ||
== 3D Structures of p73 == | == 3D Structures of p73 == | ||
| Line 17: | Line 16: | ||
[[3vd0]], [[3vd1]], [[3vd2]], [[4g82]], [[4g83]], [[4guo]], [[4guq]] – hp73 DBD + DNA<br /> | [[3vd0]], [[3vd1]], [[3vd2]], [[4g82]], [[4g83]], [[4guo]], [[4guq]] – hp73 DBD + DNA<br /> | ||
[[4a63]] – hp73 DBD + apoptosis stimulating of p53 protein<br /> | [[4a63]] – hp73 DBD + apoptosis stimulating of p53 protein<br /> | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||