4y24: Difference between revisions

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-'''Unreleased structure'''
-The entry 4y24 is ON HOLD  until Paper Publication
+==Complex of human Galectin-1 and TD-139==
+<StructureSection load='4y24' size='340' side='right' caption='[[4y24]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
-Authors: Lin, H.Y., Hsieh, T.J., Lin, C.H.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4y24]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y24 FirstGlance]. <br>
-Description: Complex of human Galectin-1 and TD-139
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TD2:3-DEOXY-3-[4-(3-FLUOROPHENYL)-1H-1,2,3-TRIAZOL-1-YL]-BETA-D-GALACTOPYRANOSYL+3-DEOXY-3-[4-(3-FLUOROPHENYL)-1H-1,2,3-TRIAZOL-1-YL]-1-THIO-BETA-D-GALACTOPYRANOSIDE'>TD2</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y1v|4y1v]], [[4y1z|4y1z]], [[4y1y|4y1y]], [[4y1u|4y1u]], [[4y1x|4y1x]], [[4y22|4y22]], [[4y20|4y20]]</td></tr>
-[[Category: Hsieh, T.J]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y24 OCA], [http://pdbe.org/4y24 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y24 RCSB], [http://www.ebi.ac.uk/pdbsum/4y24 PDBsum]</span></td></tr>
-[[Category: Lin, H.Y]]
+</table>
-[[Category: Lin, C.H]]
+== Function ==
+[[http://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Hsieh, T J]]
+[[Category: Lin, C H]]
+[[Category: Lin, H Y]]
+[[Category: Complex]]
+[[Category: Galectin-1]]
+[[Category: Sugar binding protein]]
+[[Category: Td-139]]
+[[Category: Tdg]]