Sandbox WWC6: Difference between revisions
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<scene name='69/696302/Alpha-hemolysin/1'>Alpha-hemolysin</scene> | <scene name='69/696302/Alpha-hemolysin/1'>Alpha-hemolysin</scene> | ||
Alpha hemolysins cause a partial lysis of red blood cells. | |||
The heptameric pore assembles from water-soluble subunits The transmembrane domain of this water-filled pore is primarily comprised of an anti-parallel beta-barrel | |||
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<scene name='69/696302/Beta-hemolysin/2'>Beta-hemolysin</scene> | <scene name='69/696302/Beta-hemolysin/2'>Beta-hemolysin</scene> | ||
Beta-hemolysins cause a total lysis of red blood cells. | |||
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<scene name='69/696302/Beta-hemolysin/1'>Gamma-hemolysin</scene> | <scene name='69/696302/Beta-hemolysin/1'>Gamma-hemolysin</scene> | ||
Gamma-hemolysin is both hemolytic and leukotoxic. | |||
==Pathogenic Microorganisms== | ==Pathogenic Microorganisms== | ||
Pore-forming toxins have been shown to closely relate to the pathogenicity of the toxin-producing organism <ref>http://www.ncbi.nlm.nih.gov/pubmed/1930675<ref> | Pore-forming toxins have been shown to closely relate to the pathogenicity of the toxin-producing organism <ref>http://www.ncbi.nlm.nih.gov/pubmed/1930675<ref> Both gram positive and gram negative bacteria are producers of hemolysins, as well as some clinically relevant fungi | ||
[[Image:640px-Sodium-channel.png]] | [[Image:640px-Sodium-channel.png]] | ||