4y22: Difference between revisions

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'''Unreleased structure'''


The entry 4y22 is ON HOLD  until Paper Publication
==Complex of human Galectin-1 and (3OSO3)Galbeta1-3GlcNAc==
 
<StructureSection load='4y22' size='340' side='right' caption='[[4y22]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
Authors: Lin, H.Y., Hsieh, T.J., Lin, C.H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4y22]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y22 FirstGlance]. <br>
Description: Complex of human Galectin-1 and (3OSO3)Galbeta1-3GlcNAc
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAG:BETA-METHYL-N-ACETYL-D-GLUCOSAMINE'>MAG</scene>, <scene name='pdbligand=SGA:O3-SULFONYLGALACTOSE'>SGA</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
[[Category: Hsieh, T.J]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y20|4y20]], [[4y1z|4y1z]], [[4y1x|4y1x]], [[4y1v|4y1v]], [[4y1u|4y1u]], [[4y1y|4y1y]], [[4y24|4y24]], [[4y26|4y26]]</td></tr>
[[Category: Lin, H.Y]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y22 OCA], [http://pdbe.org/4y22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y22 RCSB], [http://www.ebi.ac.uk/pdbsum/4y22 PDBsum]</span></td></tr>
[[Category: Lin, C.H]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Hsieh, T J]]
[[Category: Lin, C H]]
[[Category: Lin, H Y]]
[[Category: Complex]]
[[Category: Galectin-1]]
[[Category: Sugar binding protein]]
[[Category: Sulfated lacnac]]

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