5ckx: Difference between revisions

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-'''Unreleased structure'''
-The entry 5ckx is ON HOLD  until Paper Publication
+==Non-covalent complex of DAHP synthase and chorismate mutase from Mycobacterium tuberculosis with bound transition state analog and feedback effectors tyrosine and phenylalanine==
+<StructureSection load='5ckx' size='340' side='right' caption='[[5ckx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-Authors: Munack, S., Okvist, M., Krengel, U.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5ckx]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CKX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CKX FirstGlance]. <br>
-Description: Non-covalent complex of DAHP synthase and chorismate mutase from Mycobacterium tuberculosis with bound transition state analog and feedback effectors tyrosine and phenylalanine
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSA:8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC+ACID'>TSA</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-deoxy-7-phosphoheptulonate_synthase 3-deoxy-7-phosphoheptulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.54 2.5.1.54] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ckx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ckx OCA], [http://pdbe.org/5ckx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ckx RCSB], [http://www.ebi.ac.uk/pdbsum/5ckx PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/AROG_MYCTU AROG_MYCTU]] Catalyzes an aldol-like condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) to generate 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) and inorganic phosphate.<ref>PMID:16288916</ref>  [[http://www.uniprot.org/uniprot/CHMU_MYCTU CHMU_MYCTU]] Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.<ref>PMID:15737998</ref> <ref>PMID:18727669</ref> <ref>PMID:19556970</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
 [[Category: Krengel, U]]
 [[Category: Munack, S]]
 [[Category: Okvist, M]]
+[[Category: Chorismate mutase]]
+[[Category: Dahp-synthase]]
+[[Category: Protein complex]]
+[[Category: Shikimate pathway]]
+[[Category: Transferase-isomerase complex]]