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==Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds== | |||
<StructureSection load='4yql' size='340' side='right' caption='[[4yql]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4yql]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YQL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YQL FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4H4:4-AMINO-N-[(1S,2R)-2-(4-SULFAMOYLPHENYL)CYCLOPROPYL]-1,2,5-OXADIAZOLE-3-CARBOXAMIDE'>4H4</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ypw|4ypw]], [[4ypx|4ypx]], [[4ypz|4ypz]], [[4yq0|4yq0]], [[4yq1|4yq1]], [[4yq2|4yq2]], [[4yq3|4yq3]], [[4yq4|4yq4]], [[4yq5|4yq5]], [[4yq6|4yq6]], [[4yq7|4yq7]], [[4yq8|4yq8]], [[4yq9|4yq9]], [[4yqa|4yqa]], [[4yqb|4yqb]], [[4yqc|4yqc]], [[4yqg|4yqg]], [[4yqi|4yqi]], [[4yqj|4yqj]], [[4yqk|4yqk]], [[4yqn|4yqn]], [[4yqo|4yqo]], [[4yqp|4yqp]], [[4yqq|4yqq]], [[4yqr|4yqr]], [[4yqs|4yqs]], [[4yqt|4yqt]], [[4ypy|4ypy]]</td></tr> | ||
[[Category: Madauss, K | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yql OCA], [http://pdbe.org/4yql PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yql RCSB], [http://www.ebi.ac.uk/pdbsum/4yql PDBsum]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN]] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bonnette, W G]] | |||
[[Category: Elkins, P A]] | |||
[[Category: Madauss, K P]] | |||
[[Category: Knot]] | |||
[[Category: Sam-binding]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
[[Category: Trmd]] | |||
Revision as of 06:45, 11 May 2016
Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compoundsCrystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
Structural highlights
Function[TRMD_HAEIN] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605] |
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