5fzo

Crystal structure of the catalytic domain of human JmjD1CCrystal structure of the catalytic domain of human JmjD1C

Structural highlights 5fzo is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , , NonStd Res: Related: 5fym, 5fys, 5fyt, 5fyu, 5fyv, 5fyy, 5fyz, 5fz0, 5fz1, 5fz3, 5fz4, 5fz6, 5fz7, 5fz8, 5fz9, 5fza, 5fzb, 5fzc, 5fzd, 5fze, 5fzf, 5fzg, 5fzh, 5fzi, 5fzk, 5fzl, 5fzm Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Function [JHD2C_HUMAN] Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).

spinqualitylabelsall models 5fzo, resolution 1.84Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image