Neurophysin: Difference between revisions

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 <StructureSection load='1npo' size='340' side='right' caption='Neurophysin-2 (grey and pink) complex with oxytocin (green and yellow) (PDB code [[1npo]])' scene=''>
-'''Neurophysins''' are carrier proteins which transport hormones from the hypothalamus to the posterior pituitary gland.  Neurophysin-1 transports oxytocin and neurophysin-2 transports vasopressin.  '''Oxytocin''' is used to start labor and increase its speed.  '''Vasopressin''' functions to retain water in the body and to constrict blood vessels.
+== Function ==
+'''Neurophysins''' are carrier proteins which transport hormones from the hypothalamus to the posterior pituitary gland<ref>PMID:3147712</ref>.
-== Function ==
+*'''Neurophysin-1''' transports oxytocin.<br />
+*'''Neurophysin-2''' transports vasopressin.<br />
+*'''Oxytocin''' is used to start labor and increase its speed.<br />
+*'''Vasopressin''' functions to retain water in the body and to constrict blood vessels.
 == Disease ==
+Mutations in neurophysin-2 are associated with familial diabetes<ref>PMID:7714110</ref>.
 == Relevance ==