Sandbox WWC6: Difference between revisions
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==Structure== | ==Structure== | ||
Hemolysins have three structural variations: alpha, beta, and gamma. These hemolysin types are comprised of hepta or octomeric subunits.<ref name = "sod"/> The alpha subunit, depicted right, consists of four repeating structures, named I through IV and shown in different colors <scene name='69/696300/Right_one/1'>here</scene>. <ref name ="struct"> DOI: 10.1111/j.1469-7793.1998.647bp.x </ref> These structures consist of six transmembrane alpha helices named S1 through S6. <ref name = "struct"/> Interestingly, each repeating subunit resembles a bacterial K<sup>+</sup> channel. <ref name = "struct"/> These subunits fold together to form a central pore, and this complete structure resembles a bacterial Ca2<sup>+</sup> channel. <ref name = "struct"/> | Hemolysins have three structural variations: alpha, beta, and gamma. These hemolysin types are comprised of hepta or octomeric subunits.<ref name = "sod"/> The alpha subunit, depicted right, consists of four repeating structures, named I through IV and shown in different colors <scene name='69/696300/Right_one/1'>here</scene>. <ref name ="struct"> DOI: 10.1111/j.1469-7793.1998.647bp.x </ref> These structures consist of six transmembrane alpha helices named S1 through S6. <ref name = "struct"/> Interestingly, each repeating subunit resembles a bacterial K<sup>+</sup> channel. <ref name = "struct"/> These subunits fold together to form a central pore, and this complete structure resembles a bacterial Ca2<sup>+</sup> channel. <ref name = "struct"/> | ||
<scene name='69/696302/Beta-hemolysin/1'>Beta-hemolysin</scene> | |||
[[Image:640px-Sodium-channel.png]] | [[Image:640px-Sodium-channel.png]] | ||