Myoglobin: Difference between revisions

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<StructureSection load='1a6m' size='350' side='right' caption='Structure of Sperm whale myoglobin containing protoporphyrin with O2 and sulfate (PDB entry [[1a6m]])' scene=''>
<StructureSection load='1a6m' size='350' side='right' caption='Structure of Sperm whale myoglobin containing protoporphyrin with O2 and sulfate (PDB entry [[1a6m]])' scene=''>
__TOC__
== Function ==
== Function ==
[[Myoglobin]] is a globular protein whose function is to store molecular oxygen in muscles (myo = muscles)<ref>PMID:15339940</ref>.  It has two main components:  a single polypeptide chain, and heme ligand.  The heme ligand is only <scene name='23/238129/Transparent_spacefill/2'>partially exposed</scene> to the surface; the majority of it is buried inside the protein. The overall <scene name='23/238129/Surface/1'>shape</scene> of myoglobin is approximately disc-shaped with a diameter that is about twice its thickness.  The overall fold of the protein is conserved, especially the <scene name='23/238129/Hydrophobic/1'>hydrophobic</scene> core of the protein (shown in purple),  but the sequence is more <scene name='23/238129/Conserved_cartoon/1'>variable</scene> on the surface.  {{Template:ColorKey_ConSurf_NoYellow_NoGray}} '''Metmyoglobin''' (MMb) is the oxidized form of myoglobin.
[[Myoglobin]] is a globular protein whose function is to store molecular oxygen in muscles (myo = muscles)<ref>PMID:15339940</ref>.  It has two main components:  a single polypeptide chain, and heme ligand.  The heme ligand is only <scene name='23/238129/Transparent_spacefill/2'>partially exposed</scene> to the surface; the majority of it is buried inside the protein. The overall <scene name='23/238129/Surface/1'>shape</scene> of myoglobin is approximately disc-shaped with a diameter that is about twice its thickness.  The overall fold of the protein is conserved, especially the <scene name='23/238129/Hydrophobic/1'>hydrophobic</scene> core of the protein (shown in purple),  but the sequence is more <scene name='23/238129/Conserved_cartoon/1'>variable</scene> on the surface.  {{Template:ColorKey_ConSurf_NoYellow_NoGray}} '''Metmyoglobin''' (MMb) is the oxidized form of myoglobin.

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Karl Oberholser, Eran Hodis, Judy Voet, David Canner, Alexander Berchansky, Michal Harel, Jaime Prilusky, Eric Martz, Ann Taylor, Joel L. Sussman, Karsten Theis