MAP kinase phosphatase: Difference between revisions

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== Function ==
== Function ==
'''MAP kinase phosphatase''' (MKP) or '''Dual specificity phosphatase''' (DUSP) are phosphatases which reverse the activation of MAP kinases by dephosphorylating tyrosine or threonine residues.<br />
'''MAP kinase phosphatase''' (MKP) or '''Dual specificity phosphatase''' (DUSP) are phosphatases which reverse the activation of MAP kinases by dephosphorylating tyrosine or threonine residues<ref>PMID:18922965</ref>.<br />
*MKP-4 and MKP-5 are localized in the nucleus and cytosole<br />
*MKP-4 and MKP-5 are localized in the nucleus and cytosole<br />
*MKP-6, MKP-7 and MKP-3 are localized in the nucleus<br />
*MKP-6, MKP-7 and MKP-3 are localized in the nucleus<br />

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Michal Harel, Alexander Berchansky, Joel L. Sussman