Human growth hormone: Difference between revisions

Michal Harel (talk | contribs)
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Michal Harel (talk | contribs)
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{{STRUCTURE_1hgu|  PDB=1hgu  | SIZE=400| SCENE= |right|CAPTION=Human growth hormone (PDB code [[1hgu]])}}
{{STRUCTURE_1hgu|  PDB=1hgu  | SIZE=400| SCENE= |right|CAPTION=Human growth hormone (PDB code [[1hgu]])}}
 
==Function==
'''Human growth hormone''' (hGH) plays a vital role in growth and development. It is naturally produced by somatotropic cells in the anterior pituitary gland. The [[hormone]] is produced as a 217 amino acid precursor protein. The 26 N-terminal amino acids correspond to a signal peptide, which is essential for hormone secretion. This signal peptide is cleaved during the secretion process to yield the mature, 191 amino acid form of hGH.     
'''Human growth hormone''' (hGH) plays a vital role in growth and development. It is naturally produced by somatotropic cells in the anterior pituitary gland. The [[hormone]] is produced as a 217 amino acid precursor protein. The 26 N-terminal amino acids correspond to a signal peptide, which is essential for hormone secretion. This signal peptide is cleaved during the secretion process to yield the mature, 191 amino acid form of hGH.     


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Craig N. Streu, Michal Harel, Wayne Decatur, Joel L. Sussman, Alexander Berchansky, Ariane Clément, Clemence Cao, Clara Bayol