HOP protein: Difference between revisions

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 == Structural highlights ==
-HOP contains 3 Tpr domains which bind the C-terminal peptide EEVD of Hsp70 and Hsp90.  Tpr domain is a TetraPeptide Repeat motif of α-helix pairs involved in protein-protein adhesion.  Human HOP protein Tpr domains are: Tpr1 residues 1-118; Tpr2 residues 222-352; Tpr3 residues 356-477.
+HOP contains three Tpr domains which bind the C-terminal peptide EEVD of Hsp70 and Hsp90<ref>PMID:10786835</ref>.  Tpr domain is a TetraPeptide Repeat motif of α-helix pairs involved in protein-protein adhesion.  Human HOP protein Tpr domains are: Tpr1 residues 1-118; Tpr2 residues 222-352; Tpr3 residues 356-477.
 </StructureSection>