DNA methyltransferase: Difference between revisions
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*'''Methylcytosine DNMT''' methylates the 5 position of cytosine. <ref>PMID:8127644</ref><br /> | *'''Methylcytosine DNMT''' methylates the 5 position of cytosine. <ref>PMID:8127644</ref><br /> | ||
*'''Methyladenine DNMT''' methylates the 6 position of adenine. <ref>PMID:12732637</ref><br /> | *'''Methyladenine DNMT''' methylates the 6 position of adenine. <ref>PMID:12732637</ref><br /> | ||
*'''HhaI DNA methyltransferase''' (HDMT), a DNMT from ''Haemophilus haemolyticus'' recognizes the 5’-GCGC-3’ DNA sequence and methylates the first cytosine to convert it to 5-methylcytosine. The SAM serves as the methyl donor in the reaction and is converted to to S-adenosyl-L-homocysteine (SAH) by the reaction<ref>PMID:12139442</ref>. | |||
== Relevance == | == Relevance == | ||
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**[[2adm]] - Ta-adenine DNMT Taqi + SAM<br /> | **[[2adm]] - Ta-adenine DNMT Taqi + SAM<br /> | ||
**[[1g60]] - adenine DNMT + SAM – ''Moraxella bovis'' | **[[1g60]] - adenine DNMT + SAM – ''Moraxella bovis'' | ||
*HhaI DNA methyltransferase | |||
**[[1fjx]], [[2hmy]] – HhHDMT + SAM – ''Haemophilus haemolyticus'' <BR /> | |||
**[[1svu]] – HhHDMT (mutant) + SAH <BR /> | |||
**[[1hmy]], [[1mht]], [[3mht]], [[4mht]], [[5mht]], [[7mht]], [[8mht]], [[2hr1]], [[3eeo]] – HhHDMT + DNA + SAH <BR /> | |||
**[[2i9k]], [[2z6a]], [[2z6u]], [[2zcj]] – HhHDMT (mutant) + DNA + SAH <BR /> | |||
**[[6mht]] – HhHDMT + DNA + SAH + thiodeoxycytidine <BR /> | |||
**[[9mht]] – HhHDMT + DNA + SAH + abasic dideoxyribose <BR /> | |||
**[[1skm]] – HhHDMT + DNA + SAH + bicyclohexane <BR /> | |||
**[[10mh]] – HhHDMT + DNA + SAH + dihydroazacytosine <BR /> | |||
**[[1m0e]] – HhHDMT + DNA + SAH + zebularine <BR /> | |||
**[[2c7o]], [[2c7p]], [[2c7q]] – HhHDMT + DNA + SAH + methyl cytosine + aminopurine <BR /> | |||
**[[2c7r]] – HhHDMT (mutant) + DNA + SAH + methyl cytosine + aminopurine <BR /> | |||
**[[2z6q]] – HhHDMT (mutant) + DNA + SAH + deoxycytidine <BR /> | |||
**[[2uyc]], [[2uyh]], [[2uz4]] – HhHDMT (mutant) + DNA + SAH + methyl cytosine <BR /> | |||
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