Glycolate oxidase: Difference between revisions
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<StructureSection load='2rdu' size='350' side='right' caption='Human glycolate oxidase 1 complex with glyoxylate and FMN (PDB entry [[2rdu]])' scene=''> | <StructureSection load='2rdu' size='350' side='right' caption='Human glycolate oxidase 1 complex with glyoxylate and FMN (PDB entry [[2rdu]])' scene='48/486364/Cv/1'> | ||
== Function == | == Function == | ||
'''Glycolate oxidase''' (GOX) catalyzes the conversion of (S)-2-hydroxy acid and molecular oxygen to 2-oxo acid and hydrogen peroxide. In higher plants, GOX catalyzes the oxidation of glycolate to glyoxylate. GOX is part of the glyoxylate and dicarboxylate metabolism and uses FMN as a cofactor. GOX catalyzes the first step in the utilization of glycolate as the sole source of carbon<ref>PMID:22286136</ref>. | '''Glycolate oxidase''' (GOX) catalyzes the conversion of (S)-2-hydroxy acid and molecular oxygen to 2-oxo acid and hydrogen peroxide. In higher plants, GOX catalyzes the oxidation of glycolate to glyoxylate. GOX is part of the glyoxylate and dicarboxylate metabolism and uses FMN as a cofactor. GOX catalyzes the first step in the utilization of glycolate as the sole source of carbon<ref>PMID:22286136</ref>. | ||