Glutamate synthase: Difference between revisions
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Michal Harel (talk | contribs) New page: <StructureSection load='1ofd' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''Glutamate synthase''' (GS) catalyzes the reverse reaction which conv... |
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<StructureSection load='1llw' size='340' side='right' caption='Ferredoxin-dependent glutamate synthase containing a Fe3-S4 cluster complex with FMN, 2-oxo-glutarate (PDB code [[1llw]])' scene=''> | |||
<StructureSection load=' | |||
== Function == | == Function == | ||
'''Glutamate synthase''' (GS) catalyzes the reverse reaction which converts L-glutamine, 2-oxo-glutarate and NADPH to L-glutarate and NADP. | '''Glutamate synthase''' (GS) catalyzes the reverse reaction which converts L-glutamine, 2-oxo-glutarate and NADPH to L-glutarate and NADP. | ||
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</StructureSection> | </StructureSection> | ||
==3D structures of glutamate synthase== | |||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |||
{{#tree:id=OrganizedByTopic|openlevels=0| | |||
*Glutamate synthase | *Glutamate synthase | ||
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**[[1llz]], [[1lm1]] – SyGS + FMN <br /> | **[[1llz]], [[1lm1]] – SyGS + FMN <br /> | ||
**[[1ofe]] – SyGS + FMN + oxglutarate + oxo-norleucine<br /> | **[[1ofe]] – SyGS + FMN + oxglutarate + oxo-norleucine<br /> | ||
}} | |||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 12:13, 9 March 2016
FunctionGlutamate synthase (GS) catalyzes the reverse reaction which converts L-glutamine, 2-oxo-glutarate and NADPH to L-glutarate and NADP. [1]. Fd-dependent glutamate synthase catalyzes the reverse reaction converting L-glutamate and oxidized ferredoxin to L-glutamine, 2-oxo-glutarate and oxidized ferredoxin[2]. DiseaseRelevanceStructural highlights |
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3D structures of glutamate synthase3D structures of glutamate synthase
Updated on 09-March-2016
- Fd-dependent glutamate synthase
ReferencesReferences
- ↑ Vanoni MA, Curti B. Structure-function studies of glutamate synthases: a class of self-regulated iron-sulfur flavoenzymes essential for nitrogen assimilation. IUBMB Life. 2008 May;60(5):287-300. doi: 10.1002/iub.52. PMID:18421771 doi:http://dx.doi.org/10.1002/iub.52
- ↑ Hirasawa M, Tamura G. Flavin and iron-sulfur containing ferredoxin-linked glutamate synthase from spinach leaves. J Biochem. 1984 Apr;95(4):983-94. PMID:6746604