Galactose-binding lectin: Difference between revisions
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<StructureSection load='1v6i' size='350' side='right' caption='Structure of peanut galactose-binding lectin tetramer complex with β-D-galactose, α-D-glucose, Ca+2 (green) and Mn+2 (purple) ions (PDB entry [[1v6i]])' scene=''> | <StructureSection load='1v6i' size='350' side='right' caption='Structure of peanut galactose-binding lectin tetramer complex with β-D-galactose, α-D-glucose, Ca+2 (green) and Mn+2 (purple) ions (PDB entry [[1v6i]])' scene=''> | ||
== Function == | |||
'''Galactose-binding lectin''' (GBL) is a lectin which binds the carbohydrate sequence Gal-β(1,3)-GalNac. GBL is an all beta-sheet protein. GBL is used in affinity columns for capturing proteins which are glycosylated with Gal-β(1,3)-GalNac. | '''Galactose-binding lectin''' (GBL) is a lectin which binds the carbohydrate sequence Gal-β(1,3)-GalNac. GBL is an all beta-sheet protein<ref>PMID:17057347</ref>. | ||
== Relevance == | |||
GBL is used in affinity columns for capturing proteins which are glycosylated with Gal-β(1,3)-GalNac. | |||
</StructureSection> | </StructureSection> | ||
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**[[1l7l]], [[1uoj]] – GBL <br /> | **[[1l7l]], [[1uoj]] – GBL <br /> | ||
*'' | *''PaGBL binary complex'' | ||
**[[2wyf]] – GBL + methyl-β-galactose <br /> | **[[2wyf]] – GBL + methyl-β-galactose <br /> | ||
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**[[3zyf]], [[4a6s]] – GBL + galactopyranose derivative<br /> | **[[3zyf]], [[4a6s]] – GBL + galactopyranose derivative<br /> | ||
*'' | *''PaGBL ternary complex'' | ||
**[[3zyh]] – GBL + galactopyranose derivative + gal-lys-pro-leu <br /> | **[[3zyh]] – GBL + galactopyranose derivative + gal-lys-pro-leu <br /> | ||
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**[[4al9]] – GBL + α-D-galactose + α-D-glucose <br /> | **[[4al9]] – GBL + α-D-galactose + α-D-glucose <br /> | ||
*'' | *''PaGBL quaternary complex'' | ||
**[[2vxj]] – GBL + β-D-galactose + α-D-galactose + α-D-glucose + β-D-glucose<br /> | **[[2vxj]] – GBL + β-D-galactose + α-D-galactose + α-D-glucose + β-D-glucose<br /> | ||
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**[[2zqo]] – LtGBL C terminal + GalNac <br /> | **[[2zqo]] – LtGBL C terminal + GalNac <br /> | ||
}} | }} | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||