Sandbox Reserved 428: Difference between revisions
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. | ||
<br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br> | <br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br> | ||
<scene name='48/483885/Color1/6'> | <scene name='48/483885/Color1/6'>Amino/Carboxy Color Scene</scene> | ||
==Overall Structure== | ==Overall Structure== | ||
Revision as of 01:26, 24 February 2016
| This Sandbox is Reserved from January 19, 2016, through August 31, 2016 for use for Proteopedia Team Projects by the class Chemistry 423 Biochemistry for Chemists taught by Lynmarie K Thompson at University of Massachusetts Amherst, USA. This reservation includes Sandbox Reserved 425 through Sandbox Reserved 439. |
Vitamin D receptor/vitamin D (1db1)Vitamin D receptor/vitamin D (1db1)
by Roger Crocker, Kate Daborowski, Patrick Murphy, Benjamin Rizkin and Aaron Thole
Student Projects for UMass Chemistry 423 Spring 2016
IntroductionIntroduction
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This is a sample scene created with SAT to by Group, and another to make of the protein.
Overall StructureOverall Structure
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Binding InteractionsBinding Interactions
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Protein 1db1 is found to complex with 1,25 Dihydroxy . This molecule has three notable alcohol groups that have the ability to participate in interactions with the protein. Vitamin D3 has a large number of relations with the residues on the protein chain. First in the sequence are . Tyr143, shown in blue, is the closest to the ligand at 2.83 angstroms. This is sightly large but there is still the possibility of hydrogen bonding. Tyr147 in green and Phe150 in black are also known to have interactions with Vitamin D3 they are farther away and therefore less significant.
Additional FeaturesAdditional Features
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Outline: -Discuss mutations in Vitamin D receptor (Rickets) -Regulating hair cycle -Examine attempts to regulate Vitamin D receptor
Quiz Question 1Quiz Question 1
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See AlsoSee Also
CreditsCredits
Introduction - Kate Daborowski
Overall Structure - Aaron Thole and Benjamin Rizkin
Drug Binding Site - Roger Crocker
Additional Features - Patrick Murphy
Quiz Question 1 - name of team member