Fibroblast growth factor receptor: Difference between revisions
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<StructureSection load='1evt' size='350' side='right' scene='' caption='Human fibroblast growth factor receptor 1 ligand-binding domain modules D2 and D3 (pink and yellow) complex with fibroblast growth factor 1 ( | <StructureSection load='1evt' size='350' side='right' scene='54/544712/Cv/1' caption='Human fibroblast growth factor receptor 1 ligand-binding domain modules D2 and D3 (pink and yellow) complex with fibroblast growth factor 1 (cyan and green) and sulfate (PDB code [[1evt]]) '> | ||
== Function == | == Function == | ||
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FGFR consist of an extracellular ligand-binding domain (LBD), transmembrane helix domain and cytoplasmic tyrosine kinase activity domain (TKD) with phosphorylated tyrosine designated PTR. FGFR LBD contains 3 immunoglobulin-like domains D1, D2 and D3. | FGFR consist of an extracellular ligand-binding domain (LBD), transmembrane helix domain and cytoplasmic tyrosine kinase activity domain (TKD) with phosphorylated tyrosine designated PTR. FGFR LBD contains 3 immunoglobulin-like domains D1, D2 and D3. | ||
<scene name='54/544712/Cv/2'>Human fibroblast growth factor receptor 1 ligand-binding domain modules D2 and D3 with 2 molecules of fibroblast growth factor 1</scene> (PDB code [[1evt]]). | |||
</StructureSection> | </StructureSection> | ||
==3D structures of fibroblast growth factor receptor== | ==3D structures of fibroblast growth factor receptor== | ||