Phosphoglycerate dehydrogenase: Difference between revisions
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to a Jmol applet. Check out the other buttons as well! | to a Jmol applet. Check out the other buttons as well! | ||
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== Function == | |||
'''Phosphoglycerate dehydrogenase''' (PGDH) catalyzes the conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate. This is the first step of serine biosynthesis. NAD is used as cofactor. In some cancer cells there is an elevation in PGDH level. | '''Phosphoglycerate dehydrogenase''' (PGDH) catalyzes the conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate. This is the first step of serine biosynthesis. NAD is used as cofactor. In some cancer cells there is an elevation in PGDH level. | ||
== Structural highlights == | |||
See [[Rossmann fold]]. | |||
==3D structures of phosphoglycerate dehydrogenase== | ==3D structures of phosphoglycerate dehydrogenase== | ||