Poly(A) RNA polymerase: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='4e80' size='340' side='right' caption='Cid1 complex with UTP (stick model) (PDB code [[4e80]])' scene=''> | <StructureSection load='4e80' size='340' side='right' caption='Cid1 complex with UTP (stick model) (PDB code [[4e80]])' scene=''> | ||
== Function == | |||
'''Poly(A) RNA polymerase protein Cid1''' (Caffeine-Induced Death protein 1) is involved in cell cycle arrest where it inhibits unscheduled mitosis. Cid1 is found in fission yeast. Cid1 exists in 3 forms: apo I consists of 4 subunits; apo II consists of 2 subunits; UTP-bound form consists of 4 subunits. The UTP-bound form has in its N-terminal domain a catalytic triad of Asp residues which binds the UTP. | '''Poly(A) RNA polymerase protein Cid1''' (Caffeine-Induced Death protein 1) is involved in cell cycle arrest where it inhibits unscheduled mitosis. Cid1 is found in fission yeast. Cid1 exists in 3 forms: apo I consists of 4 subunits; apo II consists of 2 subunits; UTP-bound form consists of 4 subunits. The UTP-bound form has in its N-terminal domain a catalytic triad of Asp residues which binds the UTP. | ||
== Disease == | == Disease == | ||