Antibody: Difference between revisions

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<StructureSection load='1hzh' size='450' side='right' scene='' caption='Glycosylated human Igg with heavy chains (red and light red), light chains (aqua and green) (PDB code [[1hzh]])'>
<StructureSection load='1hzh' size='350' side='right' scene='' caption='Glycosylated human Igg with heavy chains (red and light red), light chains (aqua and green) (PDB code [[1hzh]])'>


'''Antibodies''', also known as '''Immunoglobulins''' (Ig) are gamma globulin proteins, primarily found in the blood of vertebrates.  These [[glycoproteins]] serve as a critical component of the immune system when the host fails to activate alternative compliment pathways or phagocytic cells in response to invading microorganisms or other [http://en.wikipedia.org/wiki/Antigen antigens]. The incredible specificity with which immunoglobulins bind to an antigen is based upon structural complementarity between the antigen and antibody <scene name='Antibody/1hzh_heavy_chains/1'>heavy </scene>and <scene name='Antibody/1hzh_light_chains/1'>light chains </scene>. It is this specificity that has made <scene name='Antibody/1hzh_starting_scene/3'>antibodies</scene> a critical component in laboratory and medical research.  See more in [[IgA]], [[Monoclonal Antibody]].<br />
'''Antibodies''', also known as '''Immunoglobulins''' (Ig) are gamma globulin proteins, primarily found in the blood of vertebrates.  These [[glycoproteins]] serve as a critical component of the immune system when the host fails to activate alternative compliment pathways or phagocytic cells in response to invading microorganisms or other [http://en.wikipedia.org/wiki/Antigen antigens]. The incredible specificity with which immunoglobulins bind to an antigen is based upon structural complementarity between the antigen and antibody <scene name='Antibody/1hzh_heavy_chains/1'>heavy </scene>and <scene name='Antibody/1hzh_light_chains/1'>light chains </scene>. It is this specificity that has made <scene name='Antibody/1hzh_starting_scene/3'>antibodies</scene> a critical component in laboratory and medical research.  See more in<br />
[[IgA]]<br />
[[Monoclonal Antibody]].<br />
For Anti-HIV Fab see [[Human Fab PG16]]<br />
For Anti-HIV Fab see [[Human Fab PG16]]<br />
For Anti-VEGF Fab see [[Bevacizumab]] (Avastin)<br />
For Anti-VEGF Fab see [[Bevacizumab]] (Avastin)<br />

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Eric Martz, David Canner, Wayne Decatur, Alexander Berchansky, Michal Harel, Mark Hoelzer