1fim: Difference between revisions
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|PDB= 1fim |SIZE=350|CAPTION= <scene name='initialview01'>1fim</scene>, resolution 2.2Å | |PDB= 1fim |SIZE=350|CAPTION= <scene name='initialview01'>1fim</scene>, resolution 2.2Å | ||
|SITE= | |SITE= | ||
|LIGAND= | |LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fim OCA], [http://www.ebi.ac.uk/pdbsum/1fim PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1fim RCSB]</span> | |||
}} | }} | ||
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[[Category: macrophage]] | [[Category: macrophage]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:23:40 2008'' | ||
Revision as of 20:23, 30 March 2008
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| , resolution 2.2Å | |||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
MACROPHAGE MIGRATION INHIBITORY FACTOR
OverviewOverview
The tertiary structure of the macrophage migration inhibitory factor (MIF) from rat liver (12,300 Mr) is presented at 2.2 A resolution. Each monomer consists of two beta/alpha/beta motifs aligned in quasi two-fold symmetry, comprising a domain consisting of a four-stranded mixed beta-sheet and two antiparallel alpha-helices. The protein exists as a trimer in the crystal. An extra beta-strand that is almost perpendicular to the other beta-strands joins to the beta-sheet of the neighbouring monomer in the trimer. Unexpected similarities were detected between MIF and two kinds of isomerase.
About this StructureAbout this Structure
1FIM is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
ReferenceReference
Crystal structure of the macrophage migration inhibitory factor from rat liver., Suzuki M, Sugimoto H, Nakagawa A, Tanaka I, Nishihira J, Sakai M, Nat Struct Biol. 1996 Mar;3(3):259-66. PMID:8605628
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