1e5d: Difference between revisions
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|PDB= 1e5d |SIZE=350|CAPTION= <scene name='initialview01'>1e5d</scene>, resolution 2.50Å | |PDB= 1e5d |SIZE=350|CAPTION= <scene name='initialview01'>1e5d</scene>, resolution 2.50Å | ||
|SITE= <scene name='pdbsite=FEA:Diiron+Redox+Catalytic+Site+For+Direct+Dioxygen+To+Water+...'>FEA</scene>, <scene name='pdbsite=FEB:Diiron+Redox+Catalytic+Site+For+Direct+Dioxygen+To+Water+...'>FEB</scene>, <scene name='pdbsite=FMA:Fmn+Binding+Site+For+Chain+A'>FMA</scene> and <scene name='pdbsite=FMB:Fmn+Binding+Site+For+Chain+B'>FMB</scene> | |SITE= <scene name='pdbsite=FEA:Diiron+Redox+Catalytic+Site+For+Direct+Dioxygen+To+Water+...'>FEA</scene>, <scene name='pdbsite=FEB:Diiron+Redox+Catalytic+Site+For+Direct+Dioxygen+To+Water+...'>FEB</scene>, <scene name='pdbsite=FMA:Fmn+Binding+Site+For+Chain+A'>FMA</scene> and <scene name='pdbsite=FMB:Fmn+Binding+Site+For+Chain+B'>FMB</scene> | ||
|LIGAND= <scene name='pdbligand= | |LIGAND= <scene name='pdbligand=FEO:MU-OXO-DIIRON'>FEO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e5d OCA], [http://www.ebi.ac.uk/pdbsum/1e5d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1e5d RCSB]</span> | |||
}} | }} | ||
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[[Category: Teixeira, M.]] | [[Category: Teixeira, M.]] | ||
[[Category: Xavier, A V.]] | [[Category: Xavier, A V.]] | ||
[[Category: diiron-centre]] | [[Category: diiron-centre]] | ||
[[Category: flavoprotein]] | [[Category: flavoprotein]] | ||
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[[Category: oxygenreductase]] | [[Category: oxygenreductase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:55:26 2008'' | ||
Revision as of 19:55, 30 March 2008
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| , resolution 2.50Å | |||||||
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| Sites: | , , and | ||||||
| Ligands: | , , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
RUBREDOXIN OXYGEN:OXIDOREDUCTASE (ROO) FROM ANAEROBE DESULFOVIBRIO GIGAS
OverviewOverview
Desulfovibrio gigas is a strict anaerobe that contains a well-characterized metabolic pathway that enables it to survive transient contacts with oxygen. The terminal enzyme in this pathway, rubredoxin:oxygen oxidoreductase (ROO) reduces oxygen to water in a direct and safe way. The 2.5 A resolution crystal structure of ROO shows that each monomer of this homodimeric enzyme consists of a novel combination of two domains, a flavodoxin-like domain and a Zn-beta-lactamase-like domain that contains a di-iron center for dioxygen reduction. This is the first structure of a member of a superfamily of enzymes widespread in strict and facultative anaerobes, indicating its broad physiological significance.
About this StructureAbout this Structure
1E5D is a Single protein structure of sequence from Desulfovibrio gigas. Full crystallographic information is available from OCA.
ReferenceReference
Structure of a dioxygen reduction enzyme from Desulfovibrio gigas., Frazao C, Silva G, Gomes CM, Matias P, Coelho R, Sieker L, Macedo S, Liu MY, Oliveira S, Teixeira M, Xavier AV, Rodrigues-Pousada C, Carrondo MA, Le Gall J, Nat Struct Biol. 2000 Nov;7(11):1041-5. PMID:11062560
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