1dqc: Difference between revisions
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|PDB= 1dqc |SIZE=350|CAPTION= <scene name='initialview01'>1dqc</scene> | |PDB= 1dqc |SIZE=350|CAPTION= <scene name='initialview01'>1dqc</scene> | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene> | |LIGAND= <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dqc OCA], [http://www.ebi.ac.uk/pdbsum/1dqc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dqc RCSB]</span> | |||
}} | }} | ||
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[[Category: Suetake, T.]] | [[Category: Suetake, T.]] | ||
[[Category: Tsuda, S.]] | [[Category: Tsuda, S.]] | ||
[[Category: disulfide-rich]] | [[Category: disulfide-rich]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:46:38 2008'' | ||
Revision as of 19:46, 30 March 2008
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
SOLUTION STRUCTURE OF TACHYCITIN, AN ANTIMICROBIAL PROTEIN WITH CHITIN-BINDING FUNCTION
OverviewOverview
Tachycitin, a 73-residue polypeptide having antimicrobial activity is present in the hemocyte of horseshoe crab (Tachypleus tridentatus). The first three-dimensional structure of invertebrate chitin-binding protein was determined for tachycitin using two-dimensional nuclear magnetic resonance spectroscopy. The measurements indicate that the structure of tachycitin is largely divided into N- and C-terminal domains; the former comprises a three-stranded beta-sheet and the latter a two-stranded beta-sheet following a short helical turn. The latter structural motif shares a significant tertiary structural similarity with the chitin-binding domain of plant chitin-binding protein. This result is thought to provide faithful experimental evidence to the recent hypothesis that chitin-binding proteins of invertebrates and plants are correlated by a convergent evolution process.
About this StructureAbout this Structure
1DQC is a Single protein structure of sequence from Tachypleus tridentatus. Full crystallographic information is available from OCA.
ReferenceReference
Chitin-binding proteins in invertebrates and plants comprise a common chitin-binding structural motif., Suetake T, Tsuda S, Kawabata S, Miura K, Iwanaga S, Hikichi K, Nitta K, Kawano K, J Biol Chem. 2000 Jun 16;275(24):17929-32. PMID:10770921
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