1g0w

CRYSTAL STRUCTURE OF BOVINE RETINAL CREATINE KINASECRYSTAL STRUCTURE OF BOVINE RETINAL CREATINE KINASE

Structural highlights 1g0w is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: Activity: Creatine kinase, with EC number 2.7.3.2 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Function [KCRM_BOVIN] Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed Creatine kinase (CK) catalyses the reversible transfer of the phosphate moiety from phosphocreatine (PCr) to ADP, generating creatine and ATP. The crystal structure of a cytosolic brain-type creatine kinase is reported at 2.3 A. The biological dimer sits on a crystallographic twofold axis. The N-terminal residues of both subunits come very close to the crystallographic twofold at the dimer interface. The electron density observed is consistent with two alternative conformations for the N-termini, as previously found for chicken brain-type creatine kinase. The three-dimensional structure of cytosolic bovine retinal creatine kinase.,Tisi D, Bax B, Loew A Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):187-93. PMID:11173463 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Creatine Kinase

spinqualitylabelsall models 1g0w, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image