5dsf: Difference between revisions
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''' | ==Crystal structure of the mercury-bound form of MerB mutant D99S== | ||
<StructureSection load='5dsf' size='340' side='right' caption='[[5dsf]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5dsf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DSF FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3f0p|3f0p]], [[5c0t|5c0t]], [[5c0u|5c0u]], [[5c17|5c17]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkylmercury_lyase Alkylmercury lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.2 4.99.1.2] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dsf OCA], [http://pdbe.org/5dsf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dsf RCSB], [http://www.ebi.ac.uk/pdbsum/5dsf PDBsum]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/MERB_ECOLX MERB_ECOLX]] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Alkylmercury lyase]] | |||
[[Category: Cappadocia, L]] | [[Category: Cappadocia, L]] | ||
[[Category: Lafrance-Vanasse, J]] | [[Category: Lafrance-Vanasse, J]] | ||
[[Category: Lecoq, L]] | [[Category: Lecoq, L]] | ||
[[Category: Mansour, A]] | [[Category: Mansour, A]] | ||
[[Category: Omichinski, J G]] | |||
[[Category: Stevenson, M]] | |||
[[Category: Sygusch, J]] | [[Category: Sygusch, J]] | ||
[[Category: Wahba, H M]] | |||
[[Category: Wilcox, D E]] | |||
[[Category: Wilkinson, K J]] | |||
[[Category: Lyase]] | |||
[[Category: Metal binding protein]] |