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''' | ==Crystal structure of the K499G mutant of NanB sialidase from streptococcus pneumoniae in complex with Optactin== | ||
<StructureSection load='4xma' size='340' side='right' caption='[[4xma]], [[Resolution|resolution]] 2.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4xma]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XMA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XMA FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene></td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xma OCA], [http://pdbe.org/4xma PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xma RCSB], [http://www.ebi.ac.uk/pdbsum/4xma PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Exo-alpha-sialidase]] | |||
[[Category: Brear, P]] | [[Category: Brear, P]] | ||
[[Category: Allosteric inhibitor]] | |||
[[Category: Crystallization artefact]] | |||
[[Category: Drug design]] | |||
[[Category: Glycosidase]] | |||
[[Category: Hydrolase]] | |||
[[Category: Intramolecular trans-sialidase]] | |||
[[Category: Neuraminidase]] | |||
[[Category: Serendipitous allosteric site]] | |||
Revision as of 18:49, 3 February 2016
Crystal structure of the K499G mutant of NanB sialidase from streptococcus pneumoniae in complex with OptactinCrystal structure of the K499G mutant of NanB sialidase from streptococcus pneumoniae in complex with Optactin
Structural highlights
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