DNA-protein interactions: Difference between revisions
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==DNA-Protein interactions== | ==DNA-Protein interactions== | ||
<StructureSection load='1d66' size='340' side='right' caption='Gal4 transcriptional activator interacting with its target DNA | <StructureSection load='1d66' size='340' side='right' caption='Gal4 transcriptional activator interacting with its target DNA (PDB code [[1d66]])'> | ||
__TOC__ | __TOC__ | ||
While DNA contains all the genetic material in a cell, proteins play an important role in regulating the transcription of DNA to RNA, not to mention replication, repair and packaging.. The interactions between [[DNA]] and proteins are important in this process. Most sequence specific interactions occur in the <scene name='71/711660/Grooves/1'>major grove</scene>, as the <scene name='71/711660/Base_exposure/1'>bases are exposed</scene> in this groove. In contrast, the <scene name='71/711660/Grooves/1'>minor grove</scene> contains more of the <scene name='71/711660/Base_exposure/1'>carbohydrate portions</scene> of DNA. | While DNA contains all the genetic material in a cell, proteins play an important role in regulating the transcription of DNA to RNA, not to mention replication, repair and packaging.. The interactions between [[DNA]] and proteins are important in this process. Most sequence specific interactions occur in the <scene name='71/711660/Grooves/1'>major grove</scene>, as the <scene name='71/711660/Base_exposure/1'>bases are exposed</scene> in this groove. In contrast, the <scene name='71/711660/Grooves/1'>minor grove</scene> contains more of the <scene name='71/711660/Base_exposure/1'>carbohydrate portions</scene> of DNA. | ||