Monocyte chemoattractant protein: Difference between revisions
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CCL2 is implicated in several diseases like psoriasis and rheumatoid arthritis where the appear to recruit macrophages, therefore bolstering the inflammation on joints. | CCL2 is implicated in several diseases like psoriasis and rheumatoid arthritis where the appear to recruit macrophages, therefore bolstering the inflammation on joints. | ||
It is thought to be involved in atherosclerosis in the recruitment of monocytes into the arterial wall. | It is thought to be involved in atherosclerosis in the recruitment of monocytes into the arterial wall as well as in prostate cancer<ref>PMID:25917126</ref>. | ||
It has also been found elevated in the urine of people with lupus as a sign warning of inflammation of the kidney. | It has also been found elevated in the urine of people with lupus as a sign warning of inflammation of the kidney. | ||
CCL2 is overexpressed in epilepsy, brain ischemia, Alzheimer's disease, EAE and traumatic brain injury. | CCL2 is overexpressed in epilepsy, brain ischemia, Alzheimer's disease, EAE and traumatic brain injury. | ||