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Formyl-CoA transferase: Difference between revisions

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<StructureSection load='2vjo' size='340' side='right' caption='Structure of formyl-CoA transferase complex with oxalate, CoA, HEPES buffer and Cl- ion (green) (PDB code [[2yjo]]).' scene=''>
<StructureSection load='2vjo' size='340' side='right' caption='Structure of formyl-CoA transferase complex with oxalate, CoA, HEPES buffer and Cl- ion (green) (PDB code [[2vjo]]).' scene=''>
== Function ==


'''Formyl-CoA transferase''' (FCT) catalyzes the conversion of formyl-CoA and oxalate to formate and oxalyl-CoA.  FCT takes part in the oxalate degradation pathway<ref>PMID:12839984</ref>.   
'''Formyl-CoA transferase''' (FCT) catalyzes the conversion of formyl-CoA and oxalate to formate and oxalyl-CoA.  FCT takes part in the oxalate degradation pathway<ref>PMID:12839984</ref>.   


== Function ==
== Structural highlights ==
 
== Disease ==


== Relevance ==
FCT structure shows 2 domains: large and small.  The large domain is composed of residues from the N-terminal and the C-terminal.  The active site binds CoA and oxalate <ref>PMID:18162462</ref>. 
 
== Structural highlights ==


==3D structures of formyl-CoA transferase==
==3D structures of formyl-CoA transferase==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman
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