FIS protein: Difference between revisions
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{{STRUCTURE_3jra| PDB=3jra | SIZE=400| SCENE= |right|CAPTION=FIS protein complex with DNA [[3jra]] }} | {{STRUCTURE_3jra| PDB=3jra | SIZE=400| SCENE= |right|CAPTION=FIS protein complex with DNA [[3jra]] }} | ||
'''FIS protein (Factor for Inversion Stimulation)''' is a regulatory protein in ''E. coli'' that activates ribosomal RNA transcription by binding to RNA promoter and enhances transcription by 5 to 10-fold. FIS binds to a sequence which stimulates hin-mediated DNA inversion and causes DNA bending. FIS affects the bacterial chromosome structure and the initiation of DNA replication. FIS exhibits autoregulation. It is abundant during E. coli exponential growth in rich medium and scarce during the stationary phase. | '''FIS protein (Factor for Inversion Stimulation)''' is a regulatory protein in ''E. coli'' that activates ribosomal RNA transcription by binding to RNA promoter and enhances transcription by 5 to 10-fold. FIS binds to a sequence which stimulates hin-mediated DNA inversion and causes DNA bending. FIS affects the bacterial chromosome structure and the initiation of DNA replication. FIS exhibits autoregulation. It is abundant during ''E. coli'' exponential growth in rich medium and scarce during the stationary phase<ref>PMID:11278071</ref>. | ||
== 3D Structures of FIS protein == | == 3D Structures of FIS protein == | ||
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[[1fip]] – EcFIS (mutant) + peptide <br /> | [[1fip]] – EcFIS (mutant) + peptide <br /> | ||
[[3iv5]], [[3jr9]], [[3jra]], [[3jrb]], [[3jrc]] [[3jrd]], [[3jre]], [[3jrf]], [[3jrg]], [[3jrh]], [[3jri]], [[4ihv]], [[4ihw]], [[4ihx]], [[4ihy]] – EcFIS + DNA <br /> | [[3iv5]], [[3jr9]], [[3jra]], [[3jrb]], [[3jrc]] [[3jrd]], [[3jre]], [[3jrf]], [[3jrg]], [[3jrh]], [[3jri]], [[4ihv]], [[4ihw]], [[4ihx]], [[4ihy]] – EcFIS + DNA <br /> | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 18:18, 22 January 2016
FIS protein (Factor for Inversion Stimulation) is a regulatory protein in E. coli that activates ribosomal RNA transcription by binding to RNA promoter and enhances transcription by 5 to 10-fold. FIS binds to a sequence which stimulates hin-mediated DNA inversion and causes DNA bending. FIS affects the bacterial chromosome structure and the initiation of DNA replication. FIS exhibits autoregulation. It is abundant during E. coli exponential growth in rich medium and scarce during the stationary phase[1].
3D Structures of FIS protein3D Structures of FIS protein
Updated on 22-January-2016
1fia, 3fis, 4fis, 1ety – EcFIS - Escherichia coli
1f36, 1etk, 1eto, 1etq, 1etv, 1etw, 1etx – EcFIS (mutant)
1fip – EcFIS (mutant) + peptide
3iv5, 3jr9, 3jra, 3jrb, 3jrc 3jrd, 3jre, 3jrf, 3jrg, 3jrh, 3jri, 4ihv, 4ihw, 4ihx, 4ihy – EcFIS + DNA