Exonuclease: Difference between revisions

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'''Exonucleases''' (ExN) cleave nucleotides at the end of a polynucleotide chain<ref>PMID:8747466</ref>.  In ''E. coli'' there are ExN I to VIII.<br />
'''Exonucleases''' (ExN) cleave nucleotides at the end of a polynucleotide chain<ref>PMID:14770007</ref>.  In ''E. coli'' there are ExN I to VIII. ExN were found in human and yeast as well.
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* '''ExN-I''' cleaves single-stranded DNA.<br />
* '''ExN-I''' cleaves single-stranded DNA.<br />
* '''ExN-II''' is associated with DNA polymerase.<br />
* '''ExN-II''' is associated with DNA polymerase.<br />
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* '''ExN-V''' cleaves linear double-stranded DNA.<br />
* '''ExN-V''' cleaves linear double-stranded DNA.<br />
* '''ExN-VIII''' requires a free 5’ OH group for reacting.<br />
* '''ExN-VIII''' requires a free 5’ OH group for reacting.<br />
* '''ExN''' were found in human and yeast as well.
</StructureSection>
</StructureSection>


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Michal Harel, Alexander Berchansky, Joel L. Sussman