4uee: Difference between revisions
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''' | ==Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Ala-Y(PO2CH2)-homoPhe-OH== | ||
<StructureSection load='4uee' size='340' side='right' caption='[[4uee]], [[Resolution|resolution]] 2.27Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4uee]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UEE FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LA9:(2S)-2-{[(R)-{(1R)-1-[(N-ACETYL-L-LEUCYL)AMINO]ETHYL}(HYDROXY)PHOSPHORYL]METHYL}-4-PHENYLBUTANOIC+ACID'>LA9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uef|4uef]], [[4uez|4uez]], [[4uf4|4uf4]], [[5aek|5aek]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uee OCA], [http://pdbe.org/4uee PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uee RCSB], [http://www.ebi.ac.uk/pdbsum/4uee PDBsum]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN]] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Carboxypeptidase A]] | |||
[[Category: Aviles, F X]] | |||
[[Category: Costenaro, L]] | |||
[[Category: Covaleda, G]] | |||
[[Category: Devel, L]] | |||
[[Category: Dive, V]] | [[Category: Dive, V]] | ||
[[Category: Gallego, P]] | [[Category: Gallego, P]] | ||
[[Category: Reverter, D]] | [[Category: Reverter, D]] | ||
[[Category: | [[Category: Cpa1]] | ||
[[Category: | [[Category: Hydrolase]] | ||
[[Category: | [[Category: Phosphinic inhibitor]] |