Estrogen-related receptor: Difference between revisions
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ERR plays a role in energy homeostasis and cancer<ref>PMID:16515477</ref>. ERRα and ERRγ are overexpressed in breast cancer and can serve as prognostic markers or therapeutic targets. | ERR plays a role in energy homeostasis and cancer<ref>PMID:16515477</ref>. ERRα and ERRγ are overexpressed in breast cancer and can serve as prognostic markers or therapeutic targets. | ||
== Structural insights == | |||
The chemotherapeutic drugs bisphenol and tamoxifen are nestled between 4 alpha helices in the ERR active site <ref>PMID:16990259</ref>. | |||
</StructureSection> | </StructureSection> | ||