Estrogen-related receptor: Difference between revisions

Michal Harel (talk | contribs)
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Michal Harel (talk | contribs)
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{{STRUCTURE_2gpv|  PDB=2gpv  | SIZE=400| SCENE= |right|CAPTION=Human estrogen-related receptor γ ligand-binding domain (cyan, grey, green, yellow, pink, purple) complex with nuclear receptor corepressor 2 peptide (dark red, orange) and 4-hydroxytamoxifen, [[2gpv]] }}


<StructureSection load='2gpv' size='350' side='right' scene='' caption='Human estrogen-related receptor γ ligand-binding domain (cyan, grey, green, yellow, pink, purple) complex with nuclear receptor corepressor 2 peptide (dark red, orange) and 4-hydroxytamoxifen (PDB code [[2gpv]]) '>
== Function ==


'''Estrogen-related receptor''' (ERR) binds to estrogen response elements on DNA and modulates transcription in response to [[Hormone|hormone]].  ERR plays a role in energy homeostasis and cancer.  There are 3 classes of ERR : ERRα, ERRβ and ERRγ.
'''Estrogen-related receptor''' (ERR) binds to estrogen response elements on DNA and modulates transcription in response to [[Hormone|hormone]].  There are 3 classes of ERR : ERRα, ERRβ and ERRγ.
 
== Relevance ==
 
ERR plays a role in energy homeostasis and cancer.
</StructureSection>


==3D structures of estrogen-related receptor==
==3D structures of estrogen-related receptor==
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**[[1vjb]] - mERR ligand-binding domain + 4-hydroxytamoxifen<br />
**[[1vjb]] - mERR ligand-binding domain + 4-hydroxytamoxifen<br />
}}
}}
== References ==
<references/>




[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Wayne Decatur, Alexander Berchansky