EPSP synthase: Difference between revisions

Michal Harel (talk | contribs)
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Michal Harel (talk | contribs)
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== Structural insights ==
== Structural insights ==


The enzyme has <scene name='57/570585/Two_domains/1'>two domains</scene>, with the active site found in the interdomain cleft.  There is a substantial structural change upon substrate binding, resulting in a <scene name='57/570585/Closed_formation/1'>closed formation</scene>.  Glyphosate (also known as Roundup) occupies the binding site of the second substrate, phosphoenol pyruvate.   
The enzyme has <scene name='57/570585/Two_domains/1'>two domains</scene>, with the active site found in the interdomain cleft.  There is a substantial structural change upon substrate binding, resulting in a <scene name='57/570585/Closed_formation/1'>closed formation</scene>.  '''Glyphosate''' (also known as '''Roundup''') occupies the binding site of the second substrate, phosphoenol pyruvate.   
</StructureSection>
</StructureSection>


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Ann Taylor, Michal Harel, Alexander Berchansky, Joel L. Sussman