Proteasome: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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 {{STRUCTURE_3gpt|  PDB=3gpt  | SIZE=400| SCENE= |right|CAPTION=Proteasome complex with salinosporamide derivative, [[3gpt]] }}
-[[Proteasome]] (PRTS) are large protein complexes which degrade unneeded proteins into small polypeptides.  The 26S PRTS is composed of a central 20S core particle which contains 4 stacked rings each with several members and two 19S caps.  The core particle two outer rings contain 7 α subunits which form the PRTS gate.  The two inner rings contain 6 β subunits with protease activity.  The 19S cap is composed of a base with 10 proteins six of which are ATPases and a lid which contains 9 proteins which bind polyubiquitin. The images at the left and at the right correspond to one representative Proteasome, ''i.e.'' the crystal structure of yeast Proteasome ([[3gpt]]).
+[[Proteasome]] (PRTS) are large protein complexes which degrade unneeded proteins into small polypeptides.  The 26S PRTS is composed of a central 20S core particle which contains 4 stacked rings each with several members and two 19S caps.  The core particle two outer rings contain 7 α subunits which form the PRTS gate.  The two inner rings contain 6 β subunits with protease activity.  The 19S cap is composed of a base with 10 proteins six of which are ATPases and a lid which contains 9 proteins which bind polyubiquitin. <br />
+For more details see [[3unb]].
 == 3D Structures of Proteasome ==