Dronpa: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-{{STRUCTURE_2iov|  PDB=2iov  | SIZE=400| SCENE= |right|CAPTION=Four monomers of the fluorescent protein Dronpa complex with GYC chromophore [[2iov]] }}
+{{STRUCTURE_2iov|  PDB=2iov  | SIZE=400| SCENE= |right|CAPTION=Four monomers of the fluorescent protein Dronpa complex with CYG chromophore [[2iov]] }}
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 === Function===
-Dronpa works by switching between the cis (bright state) to trans (dark state) position of a few amino acids in the chromophore center of the Beta-barrel structure.  The amino acids that are key for this change are CYG Tripeptide in the chromophore Cys 62, Tyr 63, and Gly 64.  There are also changes in conformation of four additional amino acids that are near the chromophore, Arg 66, Ser 142, Val 157, and His 193<ref> Biochem J. (2007) 402, 35-42 </ref>.
+Dronpa works by switching between the cis (bright state) to trans (dark state) position of a few amino acids in the chromophore center of the Beta-barrel structure.  The amino acids that are key for this change are CYG bicyclic chromophore which is formed spontaneously from Cys 62, Tyr 63, and Gly 64.  There are also changes in conformation of four additional amino acids that are near the chromophore, Arg 66, Ser 142, Val 157, and His 193<ref> Biochem J. (2007) 402, 35-42 </ref>.
 ==3D structures of Dronpa==