DNA methyltransferase: Difference between revisions
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Michal Harel (talk | contribs) No edit summary |
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{{STRUCTURE_1qnt| PDB=1qnt | SIZE=400| SCENE= |right|CAPTION=Human O6-methylguanine DNA methyltransferase, [[1qnt]] }} | {{STRUCTURE_1qnt| PDB=1qnt | SIZE=400| SCENE= |right|CAPTION=Human O6-methylguanine DNA methyltransferase, [[1qnt]] }} | ||
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== Function == | |||
'''DNA methyltransferase''' (DNMT) catalyzes the transfer of methyl group to DNA. Methylation is essential for gene expression. DNMT uses S-adenosyl methionine (SAM) as the methyl donor. The SAM analog S-adenosyl homocysteine (SAH) is a powerful inhibitor of DNMT. | '''DNA methyltransferase''' (DNMT) catalyzes the transfer of methyl group to DNA. Methylation is essential for gene expression. DNMT uses S-adenosyl methionine (SAM) as the methyl donor. The SAM analog S-adenosyl homocysteine (SAH) is a powerful inhibitor of DNMT. | ||