Autophagy-related protein: Difference between revisions
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<StructureSection load='3vh3' size=' | <StructureSection load='3vh3' size='350' side='right' caption='Yeast Atg7 C terminal (green) complex with Atg8 (magenta) and Zn+2 ion (grey) (PDB code [[3vh3]])' scene='70/708076/Cv/1'> | ||
'''Autophagy-related proteins''' (Atg) function in autophagosome formation from the pre-autophagosomal structure (PAS). The phagosomes perform protein degradation under starvation. Autophagy is the process of forming a vacuole around proteins or nucleic acids destined to be broken down. This vacuole is a double membrane enclosure called phagophore. Atgs have non-autophagic functions as well as they are involved in cell survival and apoptosis.<ref>PMID:26382870</ref> So far 34 Atgs have been identified in yeast. <br /> | '''Autophagy-related proteins''' (Atg) function in autophagosome formation from the pre-autophagosomal structure (PAS). The phagosomes perform protein degradation under starvation. Autophagy is the process of forming a vacuole around proteins or nucleic acids destined to be broken down. This vacuole is a double membrane enclosure called phagophore. Atgs have non-autophagic functions as well as they are involved in cell survival and apoptosis.<ref>PMID:26382870</ref> So far 34 Atgs have been identified in yeast. <br /> | ||
*'''Atg1, 6, 14''' are involved in the formation of the phagophore. <br /> | *'''Atg1, 6, 14''' are involved in the formation of the phagophore. <br /> | ||