4x38: Difference between revisions

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'''Unreleased structure'''
==Gallus interleukin-1 beta mutant - E118A==
 
<StructureSection load='4x38' size='340' side='right' caption='[[4x38]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
The entry 4x38 is ON HOLD  until Dec 09 2016
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4x38]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X38 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X38 FirstGlance]. <br>
Authors: Yin, H.S., Cheng, W.T.
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x37|4x37]], [[4x39|4x39]], [[4x3a|4x3a]]</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x38 OCA], [http://pdbe.org/4x38 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x38 RCSB], [http://www.ebi.ac.uk/pdbsum/4x38 PDBsum]</span></td></tr>
Description: Gallus interleukin-1 beta mutant -E118A
</table>
[[Category: Unreleased Structures]]
== Function ==
[[Category: Yin, H.S]]
[[http://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK]] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753]
[[Category: Cheng, W.T]]
__TOC__
</StructureSection>
[[Category: Cheng, W T]]
[[Category: Yin, H S]]
[[Category: Immune system]]

Revision as of 16:46, 9 December 2015

Gallus interleukin-1 beta mutant - E118AGallus interleukin-1 beta mutant - E118A

Structural highlights

4x38 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[O73909_CHICK] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753]

4x38, resolution 2.12Å

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