1ap0: Difference between revisions

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|ACTIVITY=  
|ACTIVITY=  
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ap0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ap0 OCA], [http://www.ebi.ac.uk/pdbsum/1ap0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ap0 RCSB]</span>
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}}


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[[Category: protein interaction motif]]
[[Category: protein interaction motif]]


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Revision as of 18:44, 30 March 2008

File:1ap0.gif


PDB ID 1ap0

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Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



STRUCTURE OF THE CHROMATIN BINDING (CHROMO) DOMAIN FROM MOUSE MODIFIER PROTEIN 1, NMR, 26 STRUCTURES


OverviewOverview

The structure of a chromatin binding domain from mouse chromatin modifier protein 1 (MoMOD1) was determined using nuclear magnetic resonance (NMR) spectroscopy. The protein consists of an N-terminal three-stranded anti-parallel beta-sheet which folds against a C-terminal alpha-helix. The structure reveals an unexpected homology to two archaebacterial DNA binding proteins which are also involved in chromatin structure. Structural comparisons suggest that chromo domains, of which more than 40 are now known, act as protein interaction motifs and that the MoMOD1 protein acts as an adaptor mediating interactions between different proteins.

About this StructureAbout this Structure

1AP0 is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

ReferenceReference

Structure of the chromatin binding (chromo) domain from mouse modifier protein 1., Ball LJ, Murzina NV, Broadhurst RW, Raine AR, Archer SJ, Stott FJ, Murzin AG, Singh PB, Domaille PJ, Laue ED, EMBO J. 1997 May 1;16(9):2473-81. PMID:9171360

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