Gluten: Difference between revisions

mNo edit summary
mNo edit summary
Line 4: Line 4:




Devin is a protein complex comprised of gliadin and glutenin. Gliadins, for those with celiac disease, are the principle toxic component of gluten and are composed of proline and glutamine-rich peptide sequences. The peptides enter the circulatory system and come into contact with [https://en.wikipedia.org/wiki/Lymphocyte lymphocytes] and [https://en.wikipedia.org/wiki/T_cell T-cells], resulting in the release of cytokines. The [https://en.wikipedia.org/wiki/Cytokine cytokines] interact with the villi of the small intestine and damage them, disabling the body from nutrient absorption. The symptoms can include abdominal pain, weight loss, fatigue, and many other symptoms associated with malnutrition. As of now, the only treatment for celiac disease is the total exclusion of gluten from the person’s diet.<ref>Celiac Disease: MedlinePlus. Retrieved October 27, 2015, from https://www.nlm.nih.gov/medlineplus/celiacdisease.html</ref><ref>Celiac Disease. Retrieved October 27, 2015, from http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/celiac-disease/Pages/facts.aspx</ref><ref>Go to Science. Retrieved October 27, 2015, from http://www.sciencemag.org/content/297/5590/2275.full</ref>
Gluten is a protein complex comprised of gliadin and glutenin. Gliadins, for those with celiac disease, are the principle toxic component of gluten and are composed of proline and glutamine-rich peptide sequences. The peptides enter the circulatory system and come into contact with [https://en.wikipedia.org/wiki/Lymphocyte lymphocytes] and [https://en.wikipedia.org/wiki/T_cell T-cells], resulting in the release of cytokines. The [https://en.wikipedia.org/wiki/Cytokine cytokines] interact with the villi of the small intestine and damage them, disabling the body from nutrient absorption. The symptoms can include abdominal pain, weight loss, fatigue, and many other symptoms associated with malnutrition. As of now, the only treatment for celiac disease is the total exclusion of gluten from the person’s diet.<ref>Celiac Disease: MedlinePlus. Retrieved October 27, 2015, from https://www.nlm.nih.gov/medlineplus/celiacdisease.html</ref><ref>Celiac Disease. Retrieved October 27, 2015, from http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/celiac-disease/Pages/facts.aspx</ref><ref>Go to Science. Retrieved October 27, 2015, from http://www.sciencemag.org/content/297/5590/2275.full</ref>


<StructureSection load='1s9v' size='450' side='right' scene ='71/716500/The_best_scene_ever_premal/1'>
<StructureSection load='1s9v' size='450' side='right' scene ='71/716500/The_best_scene_ever_premal/1'>

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Gunnar Reiske, Ben Horansky, Devin Joseph, Katlin Cannon, Premal Patel, Michal Harel, Jaime Prilusky, Alexander Berchansky, Joel L. Sussman, Eric Martz