Centromere protein: Difference between revisions
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'''Centromere proteins''' (CENP) X,S,W,T make up the kinetochore structure on chromatids where the spindle fibers attach during cell division to pull the chromatids apart. <br /> | '''Centromere proteins''' (CENP) X,S,W,T make up the kinetochore structure on chromatids where the spindle fibers attach during cell division to pull the chromatids apart. <br /> | ||
• '''CENP-X''' is a component of the Fanconi Anemia core. <br /> | • '''CENP-X''' is a component of the Fanconi Anemia core. <br /> | ||
• '''CENP-B''' facilitates centromere formation.<br /> | • '''CENP-B''' facilitates centromere formation.<ref>PMID:11726497</ref><br /> | ||
• '''CENP-A''' is a component of modified nucleosome replacing hitone H3.<br /> | • '''CENP-A''' is a component of modified nucleosome replacing hitone H3.<ref>PMID:20739937</ref><br /> | ||
• '''CENP-E''' is a motor protein involved inchromosome movement.<br /> | • '''CENP-E''' is a motor protein involved inchromosome movement.<ref>PMID:15159587</ref><br /> | ||
• '''CENP-M''' is involved in the kinetochore assembly.<br /> | • '''CENP-M''' is involved in the kinetochore assembly.<ref>PMID:25006165</ref><br /> | ||
* '''Inner centromere protein''' (INCENP) is a component of the chromosomal passenger complex which regulates mitosis. INCENP are localized at the centromeres during mid-metaphase of the cell cycle. | * '''Inner centromere protein''' (INCENP) is a component of the chromosomal passenger complex which regulates mitosis. INCENP are localized at the centromeres during mid-metaphase of the cell cycle. | ||