ATP Phosphoribosyl Transferase: Difference between revisions

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=='''HisG – ATP Phosphoribosyl Transferase'''==
=='''HisG – ATP Phosphoribosyl Transferase'''==
<applet load='1z7n' size='400' frame='true' align='right' caption='ATP phosphoribosyltransferase regulatory subunit tetramer (grey, green, pink, yellow) with ATP phosphoribosyltransferase (magenta, cyan, red, gold) complex with substrate α-phosphoribosylpyrophosphoric acid (PRPP) and phosphate, [[1z7n]]' />
<applet load='1z7n' size='350' frame='true' align='right' caption='ATP phosphoribosyltransferase regulatory subunit tetramer (grey, green, pink, yellow) with ATP phosphoribosyltransferase (magenta, cyan, red, gold) complex with substrate α-phosphoribosylpyrophosphoric acid (PRPP) and phosphate, [[1z7n]]' />


'''ATP Phosphoribosyl transferase''' (ATP-PRTase) (EC 2.4.2.17), also called '''HisG''', belongs to the enzyme super family, phosphoribosyl transferases (PRTases) and the glycosyltransferases family. It catalyzes the reversible condensation of 5-phosphoribosyl-α-1-pyrophosphate (PRPP) with ATP, yielding N’-5’-phosphoribosyl-ATP (PR-ATP) and inorganic pyrophosphate (PPi).  
'''ATP Phosphoribosyl transferase''' (ATP-PRTase) (EC 2.4.2.17), also called '''HisG''', belongs to the enzyme super family, phosphoribosyl transferases (PRTases) and the glycosyltransferases family. It catalyzes the reversible condensation of 5-phosphoribosyl-α-1-pyrophosphate (PRPP) with ATP, yielding N’-5’-phosphoribosyl-ATP (PR-ATP) and inorganic pyrophosphate (PPi).  

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Lawrence Sheringham Borketey, David Canner, Michal Harel, Alexander Berchansky