4pl6: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older editNewer edit →
No edit summary
No edit summary
Line 5: Line 5:
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pli|4pli]], [[4pll|4pll]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pli|4pli]], [[4pll|4pll]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pl6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pl6 RCSB], [http://www.ebi.ac.uk/pdbsum/4pl6 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pl6 OCA], [http://pdbe.org/4pl6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pl6 RCSB], [http://www.ebi.ac.uk/pdbsum/4pl6 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 00:07, 1 December 2015

Structure of the chromodomain of MRG2 in complex with H3K4me3Structure of the chromodomain of MRG2 in complex with H3K4me3

Structural highlights

4pl6 is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
NonStd Res:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[MRG2_ARATH] Chromatin remodeling factor. Acts as a 'reader' protein by binding to H3K4me3 and H3K36me3 to control histone H4 acetylation. Increases the transcriptional levels of the flowering time genes FLC and FT (PubMed:25183522, PubMed:25211338). Binds the chromatin at the FT promoter upon interaction with CO (PubMed:25211338).[1] [2]

References

  1. ↑ Xu Y, Gan ES, Zhou J, Wee WY, Zhang X, Ito T. Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes. Nucleic Acids Res. 2014;42(17):10960-74. doi: 10.1093/nar/gku781. Epub 2014 Sep, 2. PMID:25183522 doi:http://dx.doi.org/10.1093/nar/gku781
  2. ↑ Bu Z, Yu Y, Li Z, Liu Y, Jiang W, Huang Y, Dong AW. Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression. PLoS Genet. 2014 Sep 11;10(9):e1004617. doi: 10.1371/journal.pgen.1004617., eCollection 2014 Sep. PMID:25211338 doi:http://dx.doi.org/10.1371/journal.pgen.1004617

4pl6, resolution 1.68Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=4pl6&oldid=2499492"