CD59: Difference between revisions
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<StructureSection load='4bik' size='350' side='right' caption='Structure of human CD59 extracellular domain (green and yellow) complex with intermedilysin (grey and pink) (PDB entry [[4bik]])' scene=''> | <StructureSection load='4bik' size='350' side='right' caption='Structure of human CD59 extracellular domain (green and yellow) complex with intermedilysin (grey and pink) (PDB entry [[4bik]])' scene=''> | ||
'''CD59''' ('''Cluster of Differentiation 59''') is a protein which attaches to host cells via a GPI anchor. CD59 can prevent the formation of complement membrane attack complex via binding to complement C8 or C9. Mutations in CD59 causes disease involving thrombosis. | == Function == | ||
'''CD59''' ('''Cluster of Differentiation 59''') is a protein which attaches to host cells via a GPI anchor. CD59 can prevent the formation of complement membrane attack complex via binding to complement C8 or C9. | |||
== Disease == | |||
Mutations in CD59 causes disease involving thrombosis. | |||
==3D structures of CD59== | ==3D structures of CD59== | ||
Revision as of 14:55, 24 November 2015
<StructureSection load='4bik' size='350' side='right' caption='Structure of human CD59 extracellular domain (green and yellow) complex with intermedilysin (grey and pink) (PDB entry 4bik)' scene=>
FunctionFunction
CD59 (Cluster of Differentiation 59) is a protein which attaches to host cells via a GPI anchor. CD59 can prevent the formation of complement membrane attack complex via binding to complement C8 or C9.
DiseaseDisease
Mutations in CD59 causes disease involving thrombosis.
3D structures of CD593D structures of CD59
Updated on 24-November-2015
1erg, 1erh, 1cdq, 1cdr, 1cds – hCD59 extracellular domain – human - NMR
2ofs, 2j8b, 2uwr, 2ux2 – hCD59 extracellular domain
4bik – hCD59 extracellular domain + intermedilysin