Anthrax protective antigen: Difference between revisions
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PA contains 4 domains:<br /> | PA contains 4 domains:<br /> | ||
* Domain 1 is the N terminal. It contains the furin protease cleavage site enabling the release of PA20.<br /> | * <scene name='48/485625/Cv/3'>Domain 1 is the N terminal</scene> (yellow). It contains the furin protease cleavage site enabling the release of PA20.<br /> | ||
* Domain 2 is the heptamerization domain of PA63.<br /> | * Domain 2 is the heptamerization domain of PA63.<br /> | ||
* Domain 3 forms the heptameric pore with domain 2 and enabling LF and EF to penetrate the cell.<br /> | * Domain 3 forms the heptameric pore with domain 2 and enabling LF and EF to penetrate the cell.<br /> | ||