Barnase: Difference between revisions
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== Function == | == Function == | ||
'''Barnase''' (BA, BActerial RiboNucleASE) is a bacterial ribonuclease synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. The inhibitor barstar (BST) binds to it very tightly and prevents it from digestion of the cell’s RNA. | '''Barnase''' (BA, BActerial RiboNucleASE) is a bacterial ribonuclease synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. The inhibitor barstar (BST) binds to it very tightly and prevents it from digestion of the cell’s RNA. | ||
== Relevance == | == Relevance == | ||
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== Structural highlights == | == Structural highlights == | ||
BA hydrolyzes RNA at GpN sites where the active site positively charged Lys and Arg coordinate the RNA phosphate group. | BA hydrolyzes RNA at GpN sites where the <scene name='44/442736/Cv/3'>active site positively charged Lys and Arg coordinate the RNA phosphate group</scene>.<ref>PMID:8110767</ref> | ||
</StructureSection> | </StructureSection> | ||
Revision as of 14:13, 9 November 2015
FunctionBarnase (BA, BActerial RiboNucleASE) is a bacterial ribonuclease synthesized and secreted by the bacterium Bacillus amyloliquefaciens. The inhibitor barstar (BST) binds to it very tightly and prevents it from digestion of the cell’s RNA. RelevanceBA structure was used extensively for studying protein folding. Structural highlightsBA hydrolyzes RNA at GpN sites where the .[1]
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3D Structures of Barnase3D Structures of Barnase
Updated on 09-November-2015